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Tan Xiaojun
·Senior reproductive medicine expert
·Postdoctoral fellow at Peking University
·PhD candidate at Xiangya School of Medicine, Central South University
·Master’s tutor at Central South University
· Master's degree candidate in reproductive medicine at the University of South China
· Professional training at Huazhong University of Science and Technology and Tongji Hospital Reproductive Center
Expertise:
diagnosis and treatment of infertility, first/second/third generation IVF (including
          egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
          insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
          disease
          diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
          clinical
          technology applications. Many of these technologies are at the leading level both domestically
          and
          internationally.
Tags:
Kyrgyzstan, Tulip International Reproductive Center, Tulip Fertility Hospital, Advanced Maternal Age IVF Failure, Recurrent Implantation Failure, Third-Generation IVF (PGT)
Date:
2026.01.04
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Failed 4 Retrievals and 5 Transfers at 37? Dr. Eno Chan of Tulip International Reproductive Center Analyzes Solutions for Advanced Maternal Age

At 37, it marks a critical watershed for female fertility. Having experienced four rounds of ovulation induction and five failed transfers, the physical and psychological pressure is unimaginable for ordinary people. Faced with such a predicament, should we cut our losses or persevere? This is not just an emotional choice, but also a rational decision that requires medical data. Before making a decision, we need to first understand: why are we failing repeatedly?


Clinically, the failure of IVF with four cycles and five transfers in a 37-year-old female usually indicates two core issues: a high rate of chromosomal abnormalities in the embryos, or a problem with endometrial receptivity.


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Chen Yibing, the founder and president of Tulip International Center, pointed out:

"In our clinical practice, cases like this, where multiple cycles of ovarian stimulation and transfer have failed, are not uncommon. For a 37-year-old woman, although her ovarian reserve function may still be acceptable, the aging of oocytes is irreversible. This directly leads to a significantly increased probability of chromosomal aneuploidy in embryos. Many patients have failed in the past because they blindly transferred embryos with high appearance quality but abnormal internal chromosomes. Such embryos are not only difficult to implant, but even if they are implanted, they are highly prone to early fetal arrest and miscarriage. Therefore, for patients who have experienced repeated failures, I strongly recommend stopping the blind 'trial and error' approach to transfer and instead using preimplantation genetic testing (PGT) to screen blastocysts genetically, ensuring that the implanted embryos are truly healthy. ”


If you have repeatedly failed to conceive through conventional in vitro fertilization (IVF) in China and are facing significant economic and psychological pressures, switching tracks may be a wiser choice. Kyrgyzstan, as an emerging medical hotspot in recent years, offers new hope to numerous older couples struggling to conceive due to its friendly policies and mature technology in the field of assisted reproduction.


Tulip International Fertility Center has been deeply rooted in Kyrgyzstan for many years, boasting a mature medical team and advanced laboratory equipment. For patients who have repeatedly failed due to advanced age, Tulip Fertility Hospital adopts a more refined and personalized ovulation induction protocol, aiming to improve the utilization rate of eggs rather than simply pursuing quantity. At the same time, relying on the third-generation IVF technology, we are able to accurately eliminate embryos with chromosomal abnormalities.


In addition, if after evaluation, the patient's uterine environment is indeed no longer suitable for natural conception (such as severe intrauterine adhesions, adenomyosis, etc.), Tulip International Fertility Center can also provide legal and compliant fertility assistance programs. The legal system of Kyrgyzstan allows medically assisted fertility, which provides legal protection for families who have embryos but are unable to implant them.


In summary, 37 years old is not the end of fertility. The failure of four cycles of stimulation and five transfers indicates that the previous plan may not be suitable for your current physical condition. Don't expect different results with the same method. We recommend that you take a pause, conduct a comprehensive review and evaluation, and choose an institution like Tulip International Fertility Center that offers comprehensive solutions. Through technological upgrades or changes in assisted conception methods, there is still a chance to achieve good pregnancy.


For fertility consultation in Kyrgyzstan, please contact your dedicated consultant

/Fertility Consultation /

Dr.Chan

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