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Tan Xiaojun
·Senior reproductive medicine expert
·Postdoctoral fellow at Peking University
·PhD candidate at Xiangya School of Medicine, Central South University
·Master’s tutor at Central South University
· Master's degree candidate in reproductive medicine at the University of South China
· Professional training at Huazhong University of Science and Technology and Tongji Hospital Reproductive Center
Expertise:
diagnosis and treatment of infertility, first/second/third generation IVF (including
          egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
          insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
          disease
          diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
          clinical
          technology applications. Many of these technologies are at the leading level both domestically
          and
          internationally.
Date:
2025.10.28
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Yang Zhenning and Weng Fan's 21 Years: Love May Wait, But Fertility Cannot Wait Infinite

On October 18, 2025, Mr. Yang Zhenning passed away at the age of 103. His marriage with his wife Ms. Weng Fan, which spanned 54 years and lasted for 21 years, once again became the focus of public attention and remembrance.


This "unforgettable love" that was initially controversial and ultimately won the understanding and blessings of the world is not only a profound epic of love, but also inadvertently taught us all, especially men, a lesson on "life planning and reproductive clock".


Love that transcends time, and physiological laws that cannot be surpassed

The love between Mr. Yang Zhenning and Ms. Weng Fan proves that the union of two souls can ignore the age gap. Weng Fan wrote in his eulogy, "I am so fortunate to have his company for many years." Mr. Yang also admitted that Weng Fan was "the last gift given to me by God. Their daily life is a warmth of mutual support, a resonance between academia and art, and a pure and resilient soulmate relationship.


However, there is a realistic and unavoidable detail in this anecdote: Mr. Yang once admitted that not having children was due to his advanced age and unwillingness for Weng Fan to bear the burden of raising children alone in the future. This decision is full of love and responsibility, but it also indirectly reveals a common scientific fact that is often overlooked by men - fertility has a "shelf life".

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The 'Golden Age' and 'Silent Decline' of Male Fertility

Society generally focuses on the "reproductive clock" for women, but often overlooks the existence of an optimal reproductive age window for men (usually 25-35 years old). Beyond this window, although men still have fertility, their 'quality' has quietly declined.


Scientific evidence suggests that elderly fathers (usually aged ≥ 40) may face:


Decreased sperm quality: With age, the DNA fragmentation index (DFI) of male sperm significantly increases, which is closely related to decreased fertilization rate, poor embryo development, and increased risk of miscarriage.


Increased health risks for offspring: During the process of spermatogenesis in older fathers, the probability of new gene mutations increases, which is slightly associated with a slightly increased risk of certain spontaneous genetic diseases in offspring, such as chondrodysplasia and autism spectrum disorder.


Combined with factors such as modern lifestyle, environmental pollution, and work pressure, the average semen quality of men worldwide has already shown a downward trend. Therefore, advance planning is no longer a groundless worry, but a highly visionary self responsibility.


Real case: "Fertility Insurance" for 35 Year Old IT Elite

Background: Mark, a 35 year old engineer engaged in artificial intelligence research in Beijing, is in a period of rapid career growth, but his work intensity is extremely high, and he stays up late and works overtime all year round. He currently has no plans to get married or have children, but he is full of desire to have his own children in the future.


Concerns and Actions: Mark realizes that his lifestyle and increasing age may be "overdrawing" his future fertility potential. After consulting with experts from the Tulip International Reproductive Center, he decided to take out an "insurance" for his fertility by undergoing sperm freezing.


Process and Experience: The entire process is much simpler than he imagined. At the reproductive center of a tertiary hospital in China, he completed the preliminary screening for infectious diseases and semen analysis. Subsequently, after signing the Self Sperm Preservation Agreement, he collected several semen samples. These samples have undergone professional processing and optimization in the laboratory, and have been packaged and stored in liquid nitrogen at -196 ℃ for long-term preservation.


Mark's insight: "These few thousand dollars may be the most cost-effective investment I have made for the future. It has given me a huge psychological freedom - I can continue to pursue my career without distractions. I know that my best 'seed' has been safely stored


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Preservation of Male Fertility: A Simple and Mature 'Future Plan'

Sperm cryopreservation, also known as "self preservation", is a technically mature, safe, and reliable medical service.


Which groups of people should be given priority consideration?


Healthy men who plan to delay childbirth due to career/academic reasons.


Engaged in high-risk occupations, such as males who have long-term exposure to radiation, toxic chemicals, and high temperature environments.


Patients who are about to undergo tumor radiotherapy, chemotherapy, or other treatments that may impair fertility.


Patients with severe oligozoospermia or difficulty in sperm retrieval can be frozen in advance for emergency use.


Couples who have been living apart from each other for a long time.




Process and Cost Introduction:


Process: Prepare your ID card ->undergo a physical examination at the hospital ->sign an agreement ->collect a semen sample ->freeze and store it.


Can unmarried men do it? Absolutely possible. Unlike egg freezing, there are no restrictions on the marital status of men for self preservation of sperm in China, and unmarried men can apply with only their ID card.


The ultimate revelation: Love can transcend time, but the inheritance of life requires wise planning

Looking back at the love story between Yang Zhenning and Weng Fan, we are moved by their soulful connection and mutual fulfillment. Weng Fan once said that Mr. Yang gave her a 'pure world'; Mr. Yang, on the other hand, has been supporting each other for 21 years, guarding this belated love.


Their stories tell us that true love may come at any age. But for the continuation of life, physiological laws objectively exist. We may not be able to control when love comes, but we can use modern technology to 'seal' our best reproductive potential in advance.


At Tulip International Reproductive Center, we not only provide solutions for families facing fertility difficulties, but also advocate a forward-looking and proactive health management concept. Leave a 'backup' for your fertility, so that you can have the most precious choice on your future life path, no matter when you meet the right person or at any moment when you want to become parents.


Perhaps this is the most profound inspiration that this century's romance has given us in this era.


For fertility consultation in Kyrgyzstan, please contact your dedicated consultant

/Fertility Consultation /

Dr.Chan

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