When the AMH (anti Mullerian hormone) test value shows below 1, many women feel anxious, thinking that this indicates that the "door to fertility" is about to close.

In fact, the AMH value mainly reflects the number of eggs stored in the ovary, that is, the "inventory", rather than the absolute quality of eggs. As long as the strategy is appropriate, there is still a great opportunity to nurture a healthy life.

How should we scientifically respond to the decline in ovarian reserve function (DOR)?

Based on clinical experience, Tulip International Reproductive Center recommends that you immediately take the following three key steps.

Low AMH value, pregnancy preparation adjustment, successful assisted pregnancy

Q1: If AMH is found to be low, what other tests are needed to comprehensively evaluate the 'ovarian background'?

A doctor cannot develop an accurate diagnosis and treatment plan based solely on an AMH value. AMH is like an inventory list for a warehouse, but to understand the warehouse's shipping capacity, a comprehensive evaluation needs to be conducted in conjunction with the following checks:

Basic six hormone tests: It is usually recommended to perform blood tests on the 2nd to 3rd day of the menstrual cycle. Focus on the values of FSH (follicle stimulating hormone) and E2 (estradiol). If FSH levels are elevated (such as exceeding 10 IU/L), it usually indicates decreased ovarian function, and the response to ovulation inducing drugs may worsen.

Sinus follicle count (AFC) under transvaginal ultrasound: This is a visual indicator for evaluating ovarian reserve. Observe the number of small follicles with a diameter of 2-9mm in both ovaries through B-ultrasound. Even if AMH is low, if AFC can see a certain number of basal follicles, there is still a chance to obtain usable eggs through advanced ovulation induction technology in Kyrgyzstan.

Thyroid function and immune examination: Check for thyroid dysfunction (such as hypothyroidism, hyperthyroidism) or autoimmune antibodies, which may interfere with ovulation or affect embryo implantation.

At the Tulip International Reproductive Center, doctors will draw an accurate "fertility map" based on the above indicators to determine whether you belong to "elderly low reserve" or "young low reserve", and thus develop personalized fertility assistance plans.

Q2: How to improve egg quality through lifestyle interventions before entering the medical cycle?

Although the number of eggs is irreversible, the quality of eggs (DNA integrity, mitochondrial function) can be improved through scientific preparation for pregnancy. Before entering the assisted reproductive cycle in Kyrgyzstan, you can start from the following aspects:

Accurate nutritional support:

High quality protein: increases the intake of fish, shrimp, eggs, and lean meat, providing a material basis for follicle development.

Antioxidants: Consuming foods rich in anthocyanins and lycopene (such as blueberries and cherry tomatoes) can help resist oxidative stress and protect eggs from free radical damage.

Functional supplements: Under the guidance of a doctor, moderate supplementation of coenzyme Q10 (to improve mitochondrial function), DHEA (for some individuals with ovarian dysfunction), etc. can be administered.

Strict sleep management: Sleep is closely related to the secretion of reproductive hormones. It is recommended to go to bed before 23:00 every night to ensure 7-8 hours of high-quality sleep and utilize the natural secretion of melatonin to regulate the endocrine axis.

Moderate blood circulation exercise: Avoid overly intense exercise and recommend yoga, Pilates, or brisk walking. These exercises help improve pelvic blood circulation, increase blood perfusion to the ovaries and uterus, facilitate drug absorption and follicle growth.

Q3: What are the efficient pregnancy assistance solutions for low AMH population in Kyrgyzstan?

For women with extremely low AMH, the probability of natural conception will be significantly reduced, and time is the biggest cost. At this time, relying on the medical resources of Tulip International Reproductive Center in Kyrgyzstan, adopting assisted reproductive technology is a more efficient choice.

Micro stimulation or natural cycle regimen: For individuals with extremely low ovarian reserve, high-dose ovulation inducing drugs may not be able to obtain more eggs, but instead increase the burden on the body. Doctors may use a micro stimulation regimen to accumulate a small but high-quality amount of eggs.

Embryo accumulation strategy: If the number of eggs retrieved at a time is small, the obtained embryos can be frozen and stored through multiple retrieval cycles. After accumulating a certain number of high-quality blastocysts, transplantation or assisted reproductive procedures can be carried out to improve the success rate of a single transplantation.

Third party pregnancy assistance plan: If the uterine environment is not ideal or the body cannot bear the burden of pregnancy, under the legal framework of Kyrgyzstan, you can choose caring pregnancy assistance services, which can provide a more stable breeding environment for the baby.

Q4: Are there any real cases of successful childbirth in women with low AMH?

Case sharing: Ms. Zhou (pseudonym), 37 years old, due to long-term work pressure, examination found that AMH was only 0.68 and FSH was as high as 14. Two attempts at conventional IVF in China were unsuccessful due to slow follicle growth or empty follicles. The doctor advised her to consider egg donation, but Ms. Zhou still hopes to have a child of her own blood.

Solution: Ms. Zhou contacted Tulip International Reproductive Center and went to Kyrgyzstan.

Preprocessing: Experts suggest that she first regulate coenzyme Q10 and growth hormone.

Ovulation induction protocol: An improved PPOS protocol (ovulation induction under high progesterone status) was adopted, with egg retrieval divided into two weeks.

Three eggs were retrieved for the first time, resulting in two mature eggs and the formation of one blastocyst.

Four eggs were retrieved for the second time, resulting in three mature eggs and the formation of two blastocysts.

Genetic screening and transplantation: Perform PGT-A screening on the accumulated 3 blastocysts to obtain 1 healthy diploid embryo.

The transplantation was successful once, helping the pregnant mother to conceive smoothly. The following year, Ms. Zhou and her husband welcomed their biological son in Kyrgyzstan.

A low AMH value does not necessarily indicate the endpoint of fertility. Through scientific evaluation, lifestyle adjustments, and mature assisted reproductive technology in Kyrgyzstan, you can still seize the final opportunity. Tulip International Reproductive Center is willing to be your professional guide on the journey of reproduction, helping you realize your dreams.

For fertility consultation in Kyrgyzstan, please contact your dedicated consultant

/Fertility Consultation /

Dr.Chan

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